HPE Proliant DL380 Gen10 Plus
The industry-leading 2P/2U server is adaptable for diverse workloads and environments, providing the right balance of expandability and scalability.
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HPE Proliant DL380 Gen10 Plus
Do your servers need increased performance in storage, compute, or expansion?
The HPE ProLiant DL380 Gen10 Plus server is adaptable for diverse workloads and environments, providing you with the right balance of expandability and scalability. Designed for supreme versatility and resiliency, this 2U/2P platform is capable for deployment in multiple environments, built on 3rd Generation Intel® Xeon® Scalable Processors, and backed by a comprehensive warranty. Equipped with PCIe Gen4 capabilities, the HPE ProLiant DL380 Gen10 Plus server offers improved data transfer rates and higher networking speeds.
What's New
- Supports 3rd Generation Intel® Xeon® Scalable Processors.
- Support for PCIe Gen4, resulting in improved bandwidth and throughput.
- Support for industry-standard OCP 3.0 Network Adapters.
- Support for Trimodal (NVMe/SAS/SATA) HPE Smart Array controllers.
Key Features
Built for Some of the Most Demanding Workloads
The HPE ProLiant DL380 Gen10 Plus server is built with foundational intelligence to transform IT with insights that enhance workload performance, placement, and efficiency, delivering better outcomes faster.
Provide real-time operational feedback on server performance and recommendations for fine-tuning BIOS settings to customize for changing business needs.
360-degree Holistic Security
The HPE ProLiant DL380 Gen10 Plus server provides an enhanced, holistic, 360-degree view to security that begins in the manufacturing supply chain and concludes with a safeguarded, end-of-life decommissioning.
HPE ProLiant security begins with the corruption-free manufacture of the server and auditing the integrity of every component – hardware and firmware – to provide verification that the server begins its lifecycle uncompromised through the supply chain.
HPE ProLiant servers provide rapid detection of a security-compromised server, even to the point of not allowing it to boot, verify containment of malicious code, and protect healthy servers.
HPE ProLiant servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of operating system, application and data connections, providing the fastest path to bring a server back online and into normal operations.
When it’s time to retire or repurpose an HPE ProLiant server, one button secure erase speeds and simplifies the complete removal of passwords, configuration settings and data, preventing inadvertent access to previously secured information.
Intelligent Management Automation
The HPE ProLiant DL380 Gen10 Plus server simplifies and automates management tasks, establishing a solid foundation for an open, hybrid cloud platform enabled by composability.
Embedded in HPE servers, HPE Integrated Lights-Out (iLO) is an exclusive core intelligence that monitors server status, providing the means for reporting, ongoing management, service alerting, and local or remote management to quickly identify and resolve issues.
Automation and software defined control reduces time spent on provisioning and maintenance, as well as reduces deployment times from weeks to mere days.
HPE InfoSight for servers continually analyzes server infrastructure and applies real-world examples of hundreds of thousands of servers to predict and prevent problems before they can adversely affect business operations.
Available in an As-a-Service Experience
The HPE ProLiant DL380 Gen10 Plus server is supported by HPE GreenLake to simplify IT infrastructure management across your entire hybrid estate. With 24x7 monitoring and management, our experts do the heavy lifting to manage your environment with services built into consumption-based solutions.
Hewlett Packard Enterprise provides customers choice in how they acquire and consume IT beyond traditional financing and leasing, offering options that free trapped capital, accelerate infrastructure updates, and provide on-premises pay-per-use consumption with HPE GreenLake.
Product Images






Technical Specifications
Processor Type | Intel |
Processor Family | 3rd Generation Intel® Xeon® Scalable Processors |
Processor Core Available | 16 to 40 core, depending on model |
Maximum Memory | 8.1 TB - RDIMM (4 TB per processor), 11.2 TB - LRDIMM and Intel® Optane™ (5.6 TB per processor with 8x LRDIMM and 8x 512 GB Intel Optane) |
Memory Slots | 32 |
Memory Type | HPE DDR4 Smart Memory |
NVDIMM Type | Optional: Intel® Optane™ Persistent Memory for HPE |
NVDIMM Capacity | 128 GB - 512 GB |
Memory Protection Features | RAS – Advanced ECC, online spare, mirroring, combined channel (lockstep) functionality, and HPE Fast Fault Tolerant Memory (ADDDC); Intel Optane Persistent Memory |
Drive Supported | 8 or 12 LFF SAS/SATA/SSD 8, 10, 16, 18 or 24 SFF SAS/SATA/SSD, 2 M.2 SATA SSD standard on primary riser, depending on configuration, 8 SFF mid-tray optional, 6 SFF rear drive optional or 4 LFF mid tray optional, 3 LFF rear-drive optional and 2 SFF or 2 Dual UFF rear-drive optional, 20 SFF NVMe optional, NVMe support via Express Bay will limit maximum drive capacity, depending on model |
Network Controller | Intel I350 1GbE 4 port Base-T OCP3 adapter or Broadcom 57416 10GbE 2 port Base-T adapter and/or optional network adapters depending on model |
Remote Management Software | HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, and HPE OneView Advanced (optional, requires licenses) |
System Fan Features | Hot-plug redundant fans, standard |
Power Supply Type | Dual hot-plug redundant 1+1 HPE Flexible Slot Power Supplies (2.6”) |
Expansion Slots | 8 |
Storage Controller | HPE SR932i-p and/or HPE SR416i-a and/or HPE MR216i-a and/or HPE MR416i-a and/or HPE MR216i-p and/or HPE MR416i-p and/or HPE Smart Array P816i-a SR and/or HPE Smart Array E208i-a SR and/or HPE Smart Array P408i-a SR and/or HPE Smart Array E208i-p SR and/or HPE Smart Array E208e-p SR and/or HPE Smart Array P408e-p SR and/or HPE Smart Array P408i-p SR |
Warranty Standard Statement | Server Warranty includes 3-years parts, 3-years labor, 3-years on-site support with next business day response. Additional information regarding worldwide limited warranty and technical support is available at: www.hpe.com/services/support. Additional Hewlett Packard Enterprise support and service coverage for your product can be purchased locally. For information on availability of service upgrades and the cost for these service upgrades, refer to www.hpe.com/services/support. |
Processor Name | 3rd Generation Intel® Xeon® Scalable Processors |
Processor Number | 1 or 2 |
Processor Speed | 3.1 GHz maximum, depending on processor |
Standard Memory | 16 GB (1 x 16 GB) RDIMM |
Hard Drive Number (included) | None ship standard, SFF and LFF drives supported |
Optical Drive Type | Optional DVD-ROM Optional via Universal Media Bay External support only |
Security | Optional locking Bezel Kit, Intrusion Detection Kit, and HPE TPM 2.0 |
Form Factor | 2U |
Persistent Memory Type | Intel® Optane™ Persistent Memory for HPE |
Persistent Memory Media Capacity | 128 GB - 512 GB |
Pre-configured Models
Part Number | Model Name |
P43357-B21 | HPE ProLiant DL380 Gen10 Plus 5315Y 3.2GHz 8-core 1P 32GB-R P408i-a NC BCM57412 8SFF 800W PS Server |
P43358-B21 | HPE ProLiant DL380 Gen10 Plus 4314 2.4GHz 16-core 1P 32GB-R P408i-a NC BCM57412 8SFF 800W PS Server |
P55248-B21 | HPE ProLiant DL380 Gen10 Plus 5315Y 3.2GHz 8-core 1P 32GB-R MR416i-p NC 8SFF 800W PS Server |
P55247-B21 | HPE ProLiant DL380 Gen10 Plus 4314 2.4GHz 16-core 1P 32GB-R MR416i-p NC 8SFF 800W PS Server |
P55246-B21 | HPE ProLiant DL380 Gen10 Plus 4310 2.1GHz 12-core 1P 32GB-R MR416i-p NC 8SFF 800W PS Server |
P55245-B21 | HPE ProLiant DL380 Gen10 Plus 4309Y 2.8GHz 8-core 1P 32GB-R MR416i-p NC 8SFF 800W PS Server |
P55244-B21 | HPE ProLiant DL380 Gen10 Plus 4309Y 2.8GHz 8-core 1P 32GB-R S100i NC 8SFF 800W PS Server |
P55248-B21 | HPE ProLiant DL380 Gen10 Plus 5315Y 3.2GHz 8-core 1P 32GB-R MR416i-p NC 8SFF 800W PS EU Server |
P55247-B21 | HPE ProLiant DL380 Gen10 Plus 4314 2.4GHz 16-core 1P 32GB-R MR416i-p NC 8SFF 800W PS EU Server |
P55246-B21 | HPE ProLiant DL380 Gen10 Plus 4310 2.1GHz 12-core 1P 32GB-R MR416i-p NC 8SFF 800W PS EU Server |
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